Institute of bioinformatics and systems biology , moe key laboratory of bioinformatics department of biological sciences and biotechnology , tsinghua 生物學(xué)研究正從分子生物學(xué)走向系統(tǒng)生物學(xué),由精細(xì)的分解研究轉(zhuǎn)向系統(tǒng)的整體研究。
On the one hand , the theoretics of drug discovery become more comprehensive and more profound as the development of numerous new disciplines such as genomics , proteomics , transcriptomics , metabonomics , bioinformatics and system biology ; on the other hand , the pathways for new drug discovery are broadened by the continuous improvement of technological platforms including computer - aided drug design , high throughput screening , high content screening , biochip , transgenic and rnai technology 一方面,基因組學(xué)、蛋白質(zhì)組學(xué)、轉(zhuǎn)錄組學(xué)、代謝組學(xué)、生物信息學(xué)、系統(tǒng)生物學(xué)等新興學(xué)科的崛起與發(fā)展,為藥物發(fā)現(xiàn)提供更為廣泛而深刻的理論基礎(chǔ);另一方面,計(jì)算機(jī)輔助藥物設(shè)計(jì)、高通量篩選、高內(nèi)涵篩選、生物芯片、轉(zhuǎn)基因和rna干擾等高新技術(shù)的發(fā)展和完善,為藥物發(fā)現(xiàn)提供了新的技術(shù)手段和有力工具,極大地拓寬了藥物發(fā)現(xiàn)的途徑。